Suppression of Peroxisomal Enzyme Activities and Cytochrome P450 4A Isozyme Expression by Congeneric Polybrominated and Polychlorinated Biphenyls
نویسندگان
چکیده
منابع مشابه
Suppression of Peroxisomal Enzyme Activities and Cytochrome P450 4A Isozyme Expression by Congeneric Polybrominated and Polychlorinated Biphenyls
The purpose of this study was to determine the effects of PCBs and PBBs on peroxisome proliferator-activated receptor-alpha-(PPARalpha-) associated enzyme activities or protein levels. Male Sprague-Dawley rats were administered a single IP injection (150 mu mol/kg) of either 3,3',4,4'-tetrabromobiphenyl, 3,3',4,4'-tetrachlorobiphenyl, 3,3',5,5'-tetrabromobiphenyl, 2',3,3',4,5-pentachlorobipheny...
متن کاملCarcinogenicity of polychlorinated biphenyls and polybrominated biphenyls.
Monograph Working Group Members V J Cogliano (USA)–Chair; K Aronson, H Tryphonas (Canada); Y L Guo (Taiwan, China); M Machala (Czech Republic); E C Bonefeld-Jørgensen, K Vorkamp (Denmark) J P Cravedi, B Le Bizec, J F Narbonne (France); H Esch (Germany); P Cocco, F Merletti (Italy); R Vermeulen (unable to attend; Netherlands); A Agudo (Spain); N Johansson (Sweden); H Fiedler, N Hopf (Switzerland...
متن کاملPolychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans
This chapter was originally published in the book Veterinary Toxicology, published by Elsevier, and the attached copy is provided by Elsevier for the author’s benefit and for the benefit of the author’s institution, for non-commercial research and educational use including without limitation use in instruction at your institution, sending it to specific colleagues who know you, and providing a ...
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Polychlorinated dibenzo-p-dioxins (PCDDs) and coplanar polychlorinated biphenyls (PCBs) contribute to dioxin toxicity in humans and wildlife after bioaccumulation through the food chain from the environment. The authors examined human and rat cytochrome P450 (CYP)-dependent metabolism of PCDDs and PCBs. A number of human CYP isoforms belonging to the CYP1 and CYP2 families showed remarkable act...
متن کاملBiodegradation of Polychlorinated Biphenyls by and Isolated from Contaminated Soil
Polychlorinated biphenyls (PCBs) cause many significant ecological problems because of their low degradability, high harmfulness, and solid bioaccumulation.Two bacterial strains were isolated from soil that had been polluted with electrical transformer liquid for more than 40 years. The isolates were distinguished as Lysinibacillus macrolides DSM54Tand Bacillus firmus NBRC1530...
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ژورنال
عنوان ژورنال: PPAR Research
سال: 2007
ISSN: 1687-4757,1687-4765
DOI: 10.1155/2007/15481